Does my wife have any rights to make decisions about property willed to me by my parents?
We assume that you have title to the property in your name alone and that you are the sole owner of the property after your Mother's death.
The answer to your question depends on whether your wife has homestead rights in the property. If not, then you can sell the property without her consent. If yes, then she must sign the deed to release her homestead rights in the property.
Under Mississippi law, SEC. 89-1-29, a conveyance, mortgage, deed of trust or other incumbrance upon a homestead exempted from execution shall not be valid or binding unless signed by the spouse of the owner if the owner be married and living with the spouse.
"Homestead" generally refers to a family’s dwelling (where they reside) and the land upon which the dwelling rests.